Interoperability between phenotype and anatomy ontologies

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Interoperability between phenotype and anatomy ontologies

MOTIVATION Phenotypic information is important for the analysis of the molecular mechanisms underlying disease. A formal ontological representation of phenotypic information can help to identify, interpret and infer phenotypic traits based on experimental findings. The methods that are currently used to represent data and information about phenotypes fail to make the semantics of the phenotypic...

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The anatomy of phenotype ontologies: principles, properties and applications.

The past decade has seen an explosion in the collection of genotype data in domains as diverse as medicine, ecology, livestock and plant breeding. Along with this comes the challenge of dealing with the related phenotype data, which is not only large but also highly multidimensional. Computational analysis of phenotypes has therefore become critical for our ability to understand the biological ...

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Approaches for semantic interoperability between domain ontologies

Domain ontologies and knowledge-based systems have become very important in the agent and semantic web communities. As their use has increased, providing means of resolving semantic differences has also become very important. In this paper we survey the approaches that have been proposed for providing interoperability among domain ontologies. We also discuss some key issues that still need to b...

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Interoperability in Temporal Ontologies

In this position paper, we will discuss the interoperability between different versions of a system (an ontology). In particular, we briefly present and analyze our approach to deal with changes in ontologies. Furthermore, we discuss two open questions in the area of temporal ontologies: a) The definition of Inter-Structure Ontologies to describe the changes between two versions of an ontology ...

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 2010

ISSN: 1367-4803,1460-2059

DOI: 10.1093/bioinformatics/btq578